While the GAU-8 is iconic, are there other weapons that the A-10 could have been designed around to better fit its mission profile. One idea that comes to mind for tank-busting is a say 60mm single-barreled autocannon which would offer much more penetration against newer models of soviet tanks with the tradeoff of a much lower rate of fire and stowed rounds. Going in the opposite direction, a 30x113mm gatling would allow significant weight savings to be made at the cost of armour penetration.