@Fabius Maximus There's an important difference between the areas tended to be colonised by the Catholic powers and which tended to be colonised by the Protestants: Population density. Spain grabbed the Caribbean, Mesoamerica, and the Inca Empire, while England and the Netherlands, when they weren't simply nabbing an existing colony, took places that were relatively sparse, like the New England area and the tip of South Africa. These lead to differing colonial strategies: Spain could extract the riches of existing polities by substituting itself as the new ruling class, meaning that for them to clear out natives meant sabotaging their own ability to extract wealth. In areas like the Thirteen Colonies, meanwhile, native tribes weren't large and wealthy enough to exploit on their own, and there was little to none of the yearned-for gold and silver, forcing a strategy of cultivating cash crops using labour imported from either Europe or Africa. Because the conditions of such plantations were, of course, awful, there was a serious concern about colonists escaping to the natives and living with them rather than staying and serving the colonial company's bottom line. I can't tell you if that was
the reason for colonial elites to clear out the natives and use promises of generous land grants to keep (European) colonists from going native, but that was an effect of pushing natives into the interior.